In no particular order these things irritate me:
1 - The heroine has tiny feet.
How many people actually think of their own feet as "tiny?"
2 - The heroine falls asleep thinking about what's going to happen.
3 - The heroine has "small perfect" teeth.
4 - Jumping in and out of heads/point of view.
Do readers notice or care when we even know what the cab driver's thinking?
5 - A couple jumping into bed before I care about them - or before they care about each other. Yawn.
6 - The ending feels rushed, as though the author only had so many pages to resolve everything in.
7 - A story that starts out with so much backstory that I feel as though I've missed the previous book.
8 - Heroines who giggle.
9 - Heroines who only need a shower and a little lip gloss to look like JLo. Yeah, right.
10 - Hero's with bad attitudes and nobody ever calls them on it.
How about you?